Wanyama has been sidelined since August with a knee injury and was hopeful to return in October. However, the midfielder was required to see a specialist about the injury and it has ended up being worse than first feared.
The defensive midfielder is recovering well but manager Mauricio Pochettino doesn’t have any idea when he will be back in the team.
Belgian defender Alderweireld is expected to be out until at least the new year, after suffering a hamstring injury in the 3-1 victory over European champions Real Madrid in the UEFA Champions League at Wembley.
The club expected it to be typically one month out, but the problem was more complex and the centre back faces an extended period on the sidelines.
Pochettino says he expected injuries but believes he has a deep enough squad to cope in all competitions.
We have ahead of us a lot of games, they are not machines, But it is fantastic, we are now focusing on Lamela, Wanyama and Toby, to try be available as soon as possible and to try and help the team because we have ahead a lot of games.
But I am happy because the squad is good, the mentality is perfect.